An annual booster using distemper, hepatitis, parainfluenza, killed or modified-live virus parvovirus is given at one year of age. Thereafter, boosters are given every three years until old age. Beyond 10 years of age, booster vaccinations are generally not needed, and may be unwise if aging or other diseases are present. For animals at high exposure risk to parvovirus disease, an additional parvovirus vaccination can be given at the six-month point, if killed parvovirus is used. This extra booster is typically not needed if MLV parvovirus is used.